Health Canada has required that all generic drugs demonstrate __________ when compared to the original brand-name drug.

Question

Quizplus · Accepted Answer

Health Canada requires generic drugs to demonstrate bioequivalence to the original brand-name drug, but they do not have to demonstrate equal bioavailability. Bioequivalence means that the generic drug has the same active ingredient(s), strength, dosage form, and route of administration as the brand-name drug, and that it produces the same effects in the body within certain limits. Bioavailability refers to the rate and extent to which the active ingredient(s) are absorbed into the bloodstream and reach the intended site of action. While generic drugs do not have to have identical bioavailability to brand-name drugs, they must have similar enough bioavailability to produce the same therapeutic outcomes.

Health Canada Has Required That All Generic Drugs Demonstrate __________