Ionotropic receptors are always linked to G proteins.

Name: Ionotropic receptors are always linked to G proteins.
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Quizplus · Accepted Answer

Ionotropic receptors, also known as ligand-gated ion channels, open or close in response to binding of a specific neurotransmitter or ligand. They do not involve G proteins in their signal transduction pathway. In contrast, metabotropic receptors are linked to G proteins and trigger intracellular signaling pathways upon ligand binding.

Ionotropic Receptors Are Always Linked to G Proteins