If tolerance to a potentially toxic drug has occurred, a toxic response might occur only if the dose level is __________.

Question

Quizplus · Accepted Answer

If tolerance has occurred, the body has become accustomed to a certain level of the drug, meaning it is metabolized or eliminated more efficiently. Therefore, a higher dose may be necessary to achieve the desired effect, but if the dose level remains relatively low, it is unlikely to cause a toxic response. However, if the dose level is relatively high, it may surpass the body's capacity to metabolize or eliminate the drug, leading to a toxic response. Choice A (relatively low) is unlikely to cause a toxic response if tolerance has occurred, and choice C (virtually zero) is not applicable as no dose of the drug is being administered. Choice D (substituted by a placebo) is also not applicable as this scenario would not involve the administration of the potentially toxic drug.

If Tolerance to a Potentially Toxic Drug Has Occurred, a Toxic