Which of These Questions Would Be Most Important for a Nurse

Which of these questions would be most important for a nurse to ask when assessing a patient who is taking the herb goldenseal for cholecystitis?

A) "Do you know there are highly effective prescription medications for cholecystitis?"
B) "Are you pregnant or planning to become pregnant soon?"
C) "How did you first become aware of the use of goldenseal for cholecystitis?"
D) "Have you considered using a peppermint and goldenseal extract mixture?"