A Patient Who Is Being Treated with Topical Mafenide Acetate

A patient who is being treated with topical mafenide acetate for third-degree burns is demonstrating facial and neck edema. The nurse realizes that this patient most likely

A) is developing a hypersensitivity to the medication.
B) is reacting positively to the medication.
C) needs an increase in dosage of the medication.
D) is not responding to the medication.