Which Statement Made by a Patient Prescribed an Immunosuppressive Agent

Which statement made by a patient prescribed an immunosuppressive agent would require further teaching?

A) "I should drink a lot of fruit juices, such as grapefruit juice."
B) "I know to call the physician if I start experiencing a lot of bruising."
C) "I should drink plenty of water to keep me from getting dehydrated."
D) "If I experience any joint pain, I should take ibuprofen for the pain as needed every four hours."