A patient with sickle cell anemia has a point mutation in which the amino acid valine is incorporated into the chain instead of

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In sickle cell anemia, a point mutation in the beta-globin gene results in the substitution of valine for glutamate at position 6 in the beta-globin subunit. This substitution alters the shape of the hemoglobin molecules, causing them to stick together and form long, rigid rods that can deform red blood cells into a sickle shape.

A Patient with Sickle Cell Anemia Has a Point Mutation