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A Two-Week-Old Infant Was Seen by Her Pediatrician Because of Blistering

Question 3

Multiple Choice

A two-week-old infant was seen by her pediatrician because of blistering of the fingers and the back of her hands. The blisters were quite large and the results of the biopsy indicated that blistering occurred in the basal layer of the epidermis. The diagnosis was epidermolysis bullosa simplex. This disease is caused by mutations in the


A) tubulins
B) neurofilaments
C) G actins
D) keratins
E) chondroitins

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