A Client Has Been Prescribed Amitriptyline (Elavil)for Treatment of Depression

A client has been prescribed amitriptyline (Elavil) for treatment of depression.The nurse teaches the client to avoid use of over-the-counter sleep aids.What is the nurse's rationale for this advice?

A) Using these drugs in combination often causes bradycardia.
B) Use of amitriptyline can change enzymatic action.
C) Amitriptyline also induces sleep,so additional sleep aids are not needed.
D) Using these two medications together decreases enzyme production in the pancreas,which results in pancreatitis.