The legality of psychoactive drugs may depend on cultural and historical circumstances.

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The legality of psychoactive drugs has varied across different cultures and historical periods. Some cultures have traditional use of certain psychoactive substances, while others view them as taboo. The legal status of psychoactive drugs has also changed throughout history, with some substances that were once legal becoming illegal and vice versa. Examples include alcohol prohibition in the United States in the 1920s and the recent legalization of marijuana in some US states.

The Legality of Psychoactive Drugs May Depend on Cultural and Historical