Which of the reaction conditions would not afford the following transfromation?

Question

Quizplus · Accepted Answer

The given transformation likely involves a coupling reaction between a nucleophile and an electrophile, possibly mediated by a catalyst. Option A and B suggest the use of an amine or amide nucleophile (the NH or N functional group), while option C suggests the potential use of an organolithium reagent as the nucleophile. Therefore, all of these conditions could potentially work for the transformation. Option D, however, suggests that there are conditions that would not afford the transformation, which could include many possibilities, such as using the wrong catalyst or reactivity conditions. Without more information, option D is the best choice. Option E is not chosen because it goes against the premise of the question that there must be some specific set of conditions that would or would not work for the given transformation.

Which of the Reaction Conditions Would Not Afford the Following