The most stable conformation of cis-1-tert-butyl-2-methylcyclohexane is the one in which:

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In cyclohexane, the most stable conformation is the chair conformation, with all substituents in the equatorial position. In this case, placing the larger tert-butyl group in an axial position would lead to steric hindrance between it and the axial hydrogen atoms, leading to destabilization. The methyl group, being smaller, can fit more easily in an axial position. Therefore, the most stable conformation is where the tert-butyl group is equatorial and the methyl group is axial.

The Most Stable Conformation of Cis-1-Tert-Butyl-2-Methylcyclohexane Is the One in Which