The pH at which the concentration of the dipolar ion (zwitterion)form of an amino acid is at a maximum and the cationic and anionic forms are at equal concentrations is termed the

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The isoelectric point (pI) is the pH at which the amino acid molecule carries no net electrical charge, as the concentrations of the cationic and anionic forms are equal, resulting in the formation of the dipolar ion (zwitterion). At the isoelectric point, the amino acid is least soluble in water and exhibits its lowest electrophoretic mobility. Therefore, the isoelectric point is the term that precisely describes the pH at which the dipolar ion form of amino acids is maximized.

The PH at Which the Concentration of the Dipolar Ion