A patient with schizophrenia shows suicidal behaviors, and the provider orders clozapine [Clozaril]. The nurse teaches the family about the medication and its side effects. Which statement by a family member indicates a need for further teaching about this drug?
A) "Blood counts are necessary for several weeks after discontinuation of the drug."
B) "Fever, sore throat, and sores in the mouth should be reported immediately."
C) "If the ANC is less than 3000, the drug will be discontinued permanently."
D) "Use of this drug requires weekly evaluation of blood work."

Question

Quizplus · Accepted Answer

Clozapine can cause agranulocytosis. If the absolute neutrophil count (ANC) drops below 1000/mcL, the drug must be discontinued permanently. Blood counts must be evaluated weekly, and this evaluation should be continued for several weeks after withdrawal of the drug. Fever, sore throat, and mouth ulcers are symptoms of agranulocytosis and should be reported immediately.

A Patient with Schizophrenia Shows Suicidal Behaviors, and the Provider