The polynucleotide ligase reaction involves
A) activation of the end of a DNA strand.
B) the formation of a cyclical 2',nucleoside phosphate.
C) the intermediate formation of an anhydride linkage be- tween AMP and the 5'-phosphate of a DNA strand.
D) the intermediate formation of an ester bond between AMP and DNA.
E) the cleavage of GTP.
Correct Answer:
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