All of the Following Statements Are Correct EXCEPT Which One

All of the following statements are correct EXCEPT which one?

A) Cytochrome P450, a heme protein, reacts directly with oxygen.
B) One would expect cytochrome P450 to be inhibited by carbon monoxide.
C) NADPH, flavoprotein and an iron-sulfur protein react in sequence to reduce cytochrome P450 in some steroidogenic organs.
D) Using the heavy isotope of oxygen 18O2 it can be shown that cytochrome P450 catalyzes a reaction in which both atoms of oxygen are found in a typical product designated ROH.
E) Cytochrome P450 is located in the endoplasmic reticulum in liver, and both the endoplasmic reticulum and mitochondria in steroidogenic tissue (such as the adrenal) .