All of the following statements regarding the cytochrome P450-dependent hydroxylation of drugs are true EXCEPT which one?
A) The hydroxylation of drugs requires NADPH.
B) The oxygen atom incorporated into the drug molecule is derived from molecular oxygen.
C) The hydroxylation of drugs is associated with the utilization of protons.
D) The oxygen atom incorporated into the drug molecule is derived from water.
E) The hydroxylation of drugs is associated with the formation of water.
Correct Answer:
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