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The Toxic Form of Benzoapyrene Binds Covalently to DNA

Question 34

Multiple Choice

The toxic form of benzoapyrene binds covalently to DNA. What mechanism does benzoapyrene use to potentiate its toxicity?


A) It binds covalently to cytochrome P450
B) It increases the amount of AhR
C) It induces cytochrome P450 and its own metabolism
D) It inhibits glucuronidation
E) It inhibits its own further metabolism

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