Respiratory control refers to the striking dependence of respiration on the availability of

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Respiratory control in mitochondria is primarily regulated by the availability of ADP. This is because the process of oxidative phosphorylation, which generates ATP from ADP and inorganic phosphate, is driven by the electron transport chain's activity. When ADP levels are high, indicating a need for more ATP, respiration is stimulated to produce more ATP. Conversely, when ADP levels are low, indicating sufficient ATP supply, respiration slows down. This mechanism ensures efficient energy production according to cellular demand.

Respiratory Control Refers to the Striking Dependence of Respiration on the Availability