What effect does the chemical uncoupler 2,4-dinitrophenol have on mitochondria?

Question

Quizplus · Accepted Answer

2,4-dinitrophenol is a chemical uncoupler that disrupts the proton gradient across the inner mitochondrial membrane. This disruption allows electron transport to proceed without the synthesis of ATP, leading to an increase in oxygen consumption and heat production. As a result, the energy normally used to generate ATP is lost as heat, leading to a decrease in energy efficiency.

What Effect Does the Chemical Uncoupler 2,4-Dinitrophenol Have on Mitochondria