How does lack of oxygen in the cell decrease TCA cycle activity?

Question

Quizplus · Accepted Answer

The TCA cycle requires oxygen as the final electron acceptor in the electron transport chain to generate ATP. With a lack of oxygen, electron transport chain activity decreases and NAD+ cannot be regenerated, which limits the activity of the TCA cycle. Therefore, choice C is the best option as it explains how a lack of oxygen directly affects TCA cycle activity. Choices A, B, D, and E are not directly related to the decrease in TCA cycle activity caused by a lack of oxygen.

How Does Lack of Oxygen in the Cell Decrease TCA