All of the Following Statements Are Consistent with the Chemiosmotic

All of the following statements are consistent with the chemiosmotic hypothesis of oxidative phosphorylation EXCEPT which one?

A) Agents which uncouple oxidative phosphorylation from electron transport disrupt permeability barriers such that mitochondrial membranes become permeable to protons.
B) The term electrochemical gradient or proton gradient operationally describes the free energy generated by electron transport which drives phosphorylation of ADP.
C) Protons are transferred into the mitochondria during electron transport establishing a pH gradient.
D) Intact mitochondrial membranes are necessary for oxidative phosphorylation to occur.
E) electron carriers of the electron transport chain are vectorially oriented.