Which Krebs cycle intermediate helps to regulate the overall rate of glycolysis by direct influence on the activity of phosphofructokinase?

Question

Quizplus · Accepted Answer

Citrate is the Krebs cycle intermediate that inhibits phosphofructokinase, which is the rate-limiting enzyme in glycolysis. When there is an abundance of citrate (indicating high levels of ATP production), it signals to the cell to slow down glycolysis in order to prevent an overproduction of ATP and subsequent cell damage.

Which Krebs Cycle Intermediate Helps to Regulate the Overall Rate