Using a signal transduction pathway, glucagon influences the activity of the enzyme that catalyses the formation of

Question

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Glucagon stimulates the production of cyclic AMP (cAMP) which activates protein kinase A (PKA), which eventually leads to the phosphorylation and activation of the enzyme fructose-2,6-bisphosphatase. This enzyme catalyzes the breakdown of fructose-2,6-bisphosphate, which is a potent activator of glycolysis. Therefore, glucagon decreases the activity of glycolysis by reducing the levels of fructose-2,6-bisphosphate.

Using a Signal Transduction Pathway, Glucagon Influences the Activity of the Enzyme