Ethanol may inhibit gluconeogenesis by

Question

Quizplus · Accepted Answer

Ethanol can be metabolized in the liver by the alcohol dehydrogenase enzyme, producing NADH. This can lead to an increase in the ratio of NADH:NAD+, which can inhibit the conversion of lactate to pyruvate by lactate dehydrogenase enzyme, which in turn can inhibit gluconeogenesis. Ethanol does not directly activate glucose 6-phosphatase, inhibit pyruvate dehydrogenase, or decrease FAD in liver. While ethanol can inhibit fatty acid oxidation, this would not necessarily lead to inhibition of gluconeogenesis.

Ethanol May Inhibit Gluconeogenesis by