Net gluconeogenesis (the net synthesis of glucose) can be carried out using which of the following metabolic intermediates as a starting material? . acetyl CoA . oxaloacetate . acetoacetate . pyruvate . stearic acid

Question

Quizplus · Accepted Answer

Net gluconeogenesis can be carried out starting from oxaloacetate or pyruvate, which are both intermediates of glycolysis and the TCA cycle, respectively. Acetyl CoA and stearic acid are molecules used in lipid metabolism and cannot be directly used for gluconeogenesis. Acetoacetate can be converted to acetyl CoA, but this would not result in the net synthesis of glucose. Therefore, only options 2 and 4 (oxaloacetate and pyruvate) can be used as starting materials for gluconeogenesis.

Net Gluconeogenesis (The Net Synthesis of Glucose) Can Be Carried