In glucose 6-phosphate dehydrogenase deficiency, the associated hemolytic anemia is ultimately due to what changes from normal in red cells?

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Glucose 6-phosphate dehydrogenase deficiency leads to decreased concentrations of NADPH, which is a necessary cofactor in the glutathione pathway that helps protect red blood cells against oxidative stress. Without adequate NADPH, red blood cells are more prone to hemolysis.

In Glucose 6-Phosphate Dehydrogenase Deficiency, the Associated Hemolytic Anemia Is