The enzyme primarily responsible for generating acetyl-CoA in the cytoplasm is

Question

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Among the given options, ATP-citrate lyase is the enzyme primarily responsible for generating acetyl-CoA in the cytoplasm. This enzyme catalyzes the conversion of citrate to acetyl-CoA and oxaloacetate, thereby providing the acetyl-CoA needed for fatty acid synthesis and energy production. The other enzymes listed are involved in the citric acid cycle, gluconeogenesis or fatty acid metabolism, but not in generating acetyl-CoA in the cytoplasm.

The Enzyme Primarily Responsible for Generating Acetyl-CoA in the Cytoplasm