In the transformation of very low density lipoprotein to low density lipoprotein, one critical step is the

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Quizplus · Accepted Answer

The critical step in the transformation of VLDL to LDL is the increased hydrolysis of triacylglycerol, which leads to the loss of triacylglycerol and the generation of smaller, denser particles containing more cholesterol esters. This process is mediated by lipoprotein lipase, which is activated by apoC-II on the surface of VLDL. As triacylglycerol is hydrolyzed, VLDL is converted to intermediate density lipoprotein (IDL), which is then further metabolized to LDL by the removal of more triacylglycerol and an increased transfer of cholesterol esters from HDL. Therefore, the correct answer is E.

In the Transformation of Very Low Density Lipoprotein to Low