In the metabolism of adipose triacylglycerols, insulin stimulates the activity of each of the following proteins EXCEPT

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Quizplus · Accepted Answer

Insulin promotes the storage of fat in adipose tissue by stimulating processes like glucose uptake (via glucose transporter 4), fatty acid synthesis (via fatty acid synthase), and the uptake of fatty acids from the bloodstream (via lipoprotein lipase). It also activates 3',5'-AMP phosphodiesterase, which decreases cAMP levels, leading to a decrease in the activity of hormone-sensitive lipase. Hormone-sensitive lipase is responsible for the breakdown of stored fats into free fatty acids and glycerol, a process that insulin inhibits. Therefore, insulin does not stimulate the activity of hormone-sensitive lipase.

In the Metabolism of Adipose Triacylglycerols, Insulin Stimulates the Activity