Which Statement BEST Describes the Regulatory Action of Steroid Hormones

Which statement BEST describes the regulatory action of steroid hormones on cellular metabolic events?

A) steroid hormones serve as signals to alter cellular metabolism in response to environmental changes.
B) steroid hormones are capable of specific interactions with the genomes of their target cells.
C) steroid hormones act as an independent regulatory system relative to cyclic nucleotide systems.
D) steroid hormone action involves specificity at the levels of both cytosolic receptor and chromatin sites.
E) All of the other s are correct.