Signal transduction initiated by insulin leads to all of the following EXCEPT

Question

Quizplus · Accepted Answer

Insulin signaling does not involve activation of a G protein-coupled receptor. Instead, it binds to and activates a receptor tyrosine kinase (RTK) on the cell surface. The binding of insulin to the RTK leads to receptor dimerization and autophosphorylation, which triggers downstream signaling pathways. These pathways involve guanine nucleotide exchange, multiple protein-protein interactions, and phosphorylation of one or more proteins, ultimately leading to several cellular responses, such as increased glucose uptake, glycogen synthesis, and protein synthesis. However, insulin signaling does not directly affect secretory vesicle trafficking.

Signal Transduction Initiated by Insulin Leads to All of the Following