The formation of a soft clot (soluble fibrin) in the final stages of blood coagulation involves
A) the aggregation of fibrinopeptides A and B by end-to-end and side-to-side polymerization.
B) the action of thrombin on fibrin monomers in the presence of calcium ions.
C) a transamidation reaction between the side chains of glutamine and lysine residues catalyzed by fibrinase and calcium ions to form covalent linkages between fibrin monomers.
D) the proteolysis of fibrinogen to fibrin monomers catalyzed by fibrinase.
E) the thrombin-catalyzed conversion of fibrinogen to fibrin and the non-enzymic aggregation of fibrin monomers.
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