Activation of plasminogen to plasmin requires
A) association with lipoprotein and calcium ions.
B) specific hydrolytic cleavage to X, D, and E fragments.
C) hydrolytic cleavage by a number of proteolytic enzymes including thrombin or an activator from vascular endothelium.
D) stimulation by epsilon aminocaproic acid (EACA) .
E) circulation through the kidney and activation by a renal hormone urokinase.
Correct Answer:
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