Which are indications for discontinuing growth hormone (GH)therapy in children with documented growth hormone deficiency? (Select all that apply.)
A) Epiphyseal closure has begun.
B) A satisfactory adult height has been achieved.
C) Serum GH levels have been normal for 12 consecutive months.
D) Normal serum growth hormone levels occur.
E) The child no longer responds to the hormone.

Question

Quizplus · Accepted Answer

Treatment with GH for a child with a documented GH deficiency may continue until a satisfactory adult height has been achieved,if a child does not show a response to the hormone,or until epiphyseal closure begins. Treatment does not continue for life,and GH should not be administered during or after closure of the epiphyses. Treatment does not depend on growth hormone levels; these are measured to ensure therapeutic dosing.

Which Are Indications for Discontinuing Growth Hormone (GH)therapy in Children