A patient is taking cyclosporine [Sandimmune] and prednisone to prevent organ rejection after right renal transplantation. The patient is febrile and complains of right-sided flank pain. The nurse reviews the patient's chart and finds that the patient's BUN and serum creatinine are elevated. The cyclosporine trough is 150 ng/mL. What will the nurse do?

Question

Quizplus · Accepted Answer

The patient is showing signs of acute organ rejection,which include pain at the graft site,fever,and elevated BUN and creatinine; therefore,intravenous methylprednisolone is indicated. Because the patient is having pain on the right side,along with fever and elevated renal function test results,there is no reason to suspect that the left kidney is failing or that an infection is present. The cyclosporine level is within normal limits.

A Patient Is Taking Cyclosporine [Sandimmune] and Prednisone to Prevent