Define endochondral ossification. A)Endochondral ossification is the formation of hyaline cartilage. B)Endochondral ossification is the formation of elastic cartilage. C)Endochondral ossification is the formation of fibrocartilage. D)Endochondral ossification is the replacement of a cartilage model with bone. E)Endochondral ossification is bone formation within connective tissue without the prior development of a cartilage model.

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Endochondral ossification is the replacement of a cartilage model with bone. This process is responsible for the formation of most bones in the body, including the long bones of the limbs and the vertebrae. During endochondral ossification, cartilage cells in the model hypertrophy and die, leaving behind cavities that will eventually become the bone marrow. Blood vessels invade the area and bring in osteoblasts, which deposit a matrix of bone tissue on the remaining cartilage. Over time, this matrix calcifies and forms a bony structure that replaces the cartilage.

Define endochondral Ossification