How do abnormal antigens attached to class I MHC proteins initiate an immune response?
A)Abnormal antigens are displayed on the surface of the cell's plasma membrane and recognition by regulatory T cells initiates the initial immune response.
B)Abnormal antigens are displayed on the surface of the cell's plasma membrane and recognition by CD4 T cells initiates the initial immune response.
C)Abnormal antigens are displayed on the surface of the cell's plasma membrane and recognition by CD8 T cells initiates the initial immune response.
D)Abnormal antigens are displayed on the surface of the cell's plasma membrane and recognition by plasma cells initiates the initial immune response.
E)Abnormal antigens are displayed on the surface of the cell's plasma membrane and recognition by NK cells initiates the initial immune response.

Question

Quizplus · Accepted Answer

Abnormal antigens attached to class I MHC proteins are displayed on the surface of the infected cell's plasma membrane. Recognition of these abnormal antigens by CD8 T cells, which have specific receptors for them, initiates an immune response. CD8 T cells then differentiate into cytotoxic T lymphocytes (CTLs) that can recognize and kill infected cells. This process is known as cell-mediated immunity.

How Do Abnormal Antigens Attached to Class I MHC Proteins