The following are the steps involved in transmission at a cholinergic synapse. 1.Chemically gated sodium channels on the postsynaptic membrane are activated.
2)Calcium ions enter the synaptic knob.
3)Acetylcholinesterase hydrolyzes acetylcholine.
4)An action potential depolarizes the synaptic knob at the presynaptic membrane.
5)The synaptic knob reabsorbs choline.
6)Acetylcholine is released from storage vesicles by exocytosis.
7)Acetylcholine binds to receptors on the postsynaptic membrane.
8)Calcium ions are removed from the cytoplasm of the synaptic knob.
What is the proper sequence of these events?
A)4,2,6,7,8,5,3,1
B)4,2,6,7,1,8,3,5
C)2,4,6,7,1,8,3,5
D)2,5,4,6,7,1,8,3
E)6,4,2,7,1,8,3,5

Question

Quizplus · Accepted Answer

The correct sequence for transmission at a cholinergic synapse starts with the depolarization of the synaptic knob (4), followed by the entry of calcium ions (2), which triggers the release of acetylcholine (6). Acetylcholine then binds to receptors on the postsynaptic membrane (7), leading to the activation of chemically gated sodium channels (1). Subsequently, calcium ions are removed from the cytoplasm of the synaptic knob (8), acetylcholinesterase hydrolyzes acetylcholine (3), and the synaptic knob reabsorbs choline (5) for the synthesis of new acetylcholine molecules.

The Following Are the Steps Involved in Transmission at a Cholinergic