Which Is Not Correct Regarding the Development of the Endocrine

Which is not correct regarding the development of the endocrine system?

A) The adrenal medulla develops from neural crest cells.
B) The hypophyseal pouch and neurohypophyseal bud combine to form the pituitary gland.
C) The thyroid gland becomes functional by weeks 10-12 of development.
D) The thyroid gland initially forms as a mass that is part of the developing tongue.
E) The adrenal cortex has portions derived from all three embryonic germ layers.