The primary reason for evaluating alpha-fetoprotein (AFP)levels in maternal serum is to determine if the fetus has
A) hemophilia.
B) a neural tube defect.
C) sickle cell anemia.
D) a normal lecithin/sphingomyelin (L/S) ratio.

Question

Quizplus · Accepted Answer

An open neural tube allows a high level of AFP to seep into the amniotic fluid and enter the maternal serum.Hemophilia is a genetic defect and is best detected with chromosomal studies such as chorionic villus sampling or amniocentesis.Sickle cell is a genetic defect and is best detected with chromosomal studies such as chorionic villus sampling or amniocentesis.L/S ratios are determined with an amniocentesis,which is usually done in the third trimester.

The Primary Reason for Evaluating Alpha-Fetoprotein (AFP)levels in Maternal Serum