Which of these substances can lead to miscarriage,preterm labor,placental separation (abruption),and stillbirth?

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Cocaine is a powerful CNS stimulant.Effects on pregnancy associated with cocaine use include abruptio placentae,preterm labor,precipitous birth,and stillbirth.Heroin is an opiate.Its use in pregnancy is associated with preeclampsia,intrauterine growth restriction,miscarriage,premature rupture of membranes,infections,breech presentation,and preterm labor.The most serious effect of alcohol use in pregnancy is FAS.The major concerns regarding PCP use in pregnant women are its association with polydrug abuse and the neurobehavioral effects on the neonate.

Which of These Substances Can Lead to Miscarriage,preterm Labor,placental Separation