While Instructing a Patient on Pain Relief, the Nurse Uses

While instructing a patient on pain relief, the nurse uses the example of endorphins as endocrine hormones, which act locally at the site of injury. The nurse is explaining what route of hormone transport in the body?

A) paracrine method
B) direct release into the bloodstream
C) neuroendocrine route
D) nerve cell extension into the posterior pituitary