The nurse on the transplant unit is reviewing assessment data for a group of patients. Which patients should the nurse realize are at greatest risk for graft-versus-host disease? $\begin{array}{|l|l|c|l|c|}
\hline& {\text { Patient A }} & \text { Patient B } & {\text { Patient C }} & {\text { Patient D }} \
\hline \text { Transplant }&\text { Kidney } & \text { Bone Marrow } & \text { Liver } & \text { Lung } \
\hline \text { Time frame post }&\text { 2 days post } & \text { 2 months post } & 3 \text { months post } & 6 \text { months } \
\text { transplant }&&&&\text { post }\
\hline \text { Symptoms/diagnostics }& \begin{array}{r}
\text { Diagnostic } \
\text { studies }
\end{array} & \text { Rash on } & \text { Nausea, } & \text { Inereasing } \
\text { Present }&\text { reveal poor } & \text { hands and } & \text { abdominal } & \text { dyspnea } \
&\text { perfusion to } & \text { soles of } & \text { bloody } & \text { and fever } \
&\text { renal vessels } & \text { feet. } & \text { diarrhea } & \
\hline
\end{array}$

Question

The nurse on the transplant unit is reviewing assessment data for a group of patients. Which patients should the nurse realize are at greatest risk for graft-versus-host disease? $\begin{array}{|l|l|c|l|c|}
\hline& {\text { Patient A }} & \text { Patient B } & {\text { Patient C }} & {\text { Patient D }} \
\hline \text { Transplant }&\text { Kidney } & \text { Bone Marrow } & \text { Liver } & \text { Lung } \
\hline \text { Time frame post }&\text { 2 days post } & \text { 2 months post } & 3 \text { months post } & 6 \text { months } \
\text { transplant }&&&&\text { post }\
\hline  \text { Symptoms/diagnostics }& \begin{array}{r}
\text { Diagnostic } \
\text { studies }
\end{array} & \text { Rash on } & \text { Nausea, } & \text { Inereasing } \
\text { Present }&\text { reveal poor } & \text { hands and } & \text { abdominal } & \text { dyspnea } \
&\text { perfusion to } & \text { soles of } & \text { bloody } & \text { and fever } \
&\text { renal vessels } & \text { feet. } & \text { diarrhea } & \
\hline
\end{array}$

Quizplus · Accepted Answer

Graft-versus-host disease (GVHD) is a condition that occurs after an allogeneic transplant when the donated bone marrow or peripheral blood stem cells view the recipient's body as foreign and attack it. Patient B, who received a bone marrow transplant and is experiencing a rash on the hands and soles of the feet, is showing classic symptoms of GVHD. Kidney, liver, and lung transplants do not typically involve the immune system attacking the host in the same way, making GVHD primarily a concern with bone marrow or stem cell transplants.

The Nurse on the Transplant Unit Is Reviewing Assessment Data