During an Assessment a Patient with Multiple Substance Addictions Asks

During an assessment a patient with multiple substance addictions asks why the need for drugs and alcohol is so great. What should the nurse include when responding to this patient?

A) "Substance abuse is sign of weakness and boredom with life."
B) "Alcohol reinforces the transmission of opioids in the system."
C) "There is a human tendency to seek pleasure and avoid stress and pain."
D) "It really depends upon genetic makeup and if your parents used drugs."
E) "One substance in the brain, dopamine, is responsible for drug-seeking behavior."