In 1933, the U.S.Congress repealed the Eighteenth Amendment,

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The Eighteenth Amendment had prohibited the sale, manufacture, and transportation of alcohol, thus creating the era known as Prohibition. When the Eighteenth Amendment was repealed in 1933 with the ratification of the Twenty-first Amendment, it brought an end to Prohibition and made the sale and consumption of alcohol legal again. The repeal of the Eighteenth Amendment did not legalize any drugs, including opiate-derivative drugs, heroin, or morphine. It also did not prohibit the sale of tobacco products to minors, as there was no federal law regulating the sale of tobacco to minors at the time.

In 1933, the U.S.Congress Repealed the Eighteenth Amendment