A child with non-Hodgkin lymphoma will be starting chemotherapy.What intervention is initiated before chemotherapy to prevent tumor lysis syndrome?

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Intensive hydration with an IV fluid containing bicarbonate alkalinizes the urine to help prevent the formation of uric acid crystals,which damage the kidney.A central venous catheter is placed to assist in delivering chemotherapy.An externalized VP shunt may be placed to relieve intracranial pressure caused by a brain tumor.If a splenectomy is necessary for a child with Hodgkin disease,the pneumococcal and Haemophilus influenzae vaccines are administered before the surgery.

A Child with Non-Hodgkin Lymphoma Will Be Starting Chemotherapy