Because X-linked disorders are essentially __________, they will only appear in the __________ sex.
A) autonomic recessive disorders/ homogametic
B) autonomic dominant disorders/ homogametic
C) autonomic recessive disorders/ heterogametic
D) autonomic dominant disorders/ heterogametic

Question

Quizplus · Accepted Answer

X-linked disorders are caused by mutations in genes located on the X chromosome. Since males only have one X chromosome, they are considered hemizygous for X-linked genes. Females have two X chromosomes, and can be either homozygous or heterozygous for X-linked genes. Because X-linked disorders are recessive, they will only appear in individuals who have two copies of the mutated gene. In females, this means that both X chromosomes must carry the mutation (homozygous), while in males, the single X chromosome must carry the mutation (hemizygous). Therefore, X-linked disorders will only appear in the heterogametic (i.e. sex with two different sex chromosomes) sex, which is males in this case.

Because X-Linked Disorders Are Essentially __________, They Will Only Appear