How Effective Was the Universal Inquisition Established by the Papacy

How effective was the Universal Inquisition established by the papacy in 1542?

A) The Inquisition was filled with internal rivalries and conflicts that prevented it from effectively working outside of a few famous cases.
B) The Inquisition effectively destroyed heresy within the Papal States but had little influence elsewhere.
C) The Inquisition had considerable success in all Catholic lands where political leaders supported it.
D) The Inquisition's success at rooting out heresy was so effective that many Protestant leaders invited it to work in Protestant lands.