With respect to the link between stress and the onset of manic and depressive episodes, it appears that

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Research suggests that different types of stress may be linked to the onset of manic and depressive episodes. For example, interpersonal stress (such as conflict in relationships) may be more closely linked to depressive episodes, while goal-oriented stress (such as work or academic pressure) may be more closely linked to manic episodes.

With Respect to the Link Between Stress and the Onset